9VA8

Crystal Structure of Human Cathepsin B with a L-peptide substrate

Summary for 9VA8

• Entry DOI: 10.2210/pdb9va8/pdb
• Descriptor: Cathepsin B, (ACE)YY(F3V) (3 entities in total)
• Functional Keywords: covalent inhibitor, peptide binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 28236.46

Authors

Li, M.,Li, T.,Chen, K. (deposition date: 2025-06-03, release date: 2026-05-06)

• Primary citation: Li, M.,Chen, K.,Zhang, W.,Han, J.,Guo, M.,Zhu, X.,Zheng, J.,Li, T.,Dang, B.; Transcending stereochemical boundaries: ambidextrous cleavage of D- and L-peptide enantiomers by natural eukaryotic proteases; Vita, 2026; DOI: 10.15302/vita.2026.03.0022

Experimental method

X-RAY DIFFRACTION (1.5 Å)