9V9Q

Cryo-EM structure of the cPRC1-UbcH5c E3-E2 complex bound to the H2BK120ub-modified nucleosome

Summary for 9V9Q

• Entry DOI: 10.2210/pdb9v9q/pdb
• EMDB information: 64884
• Descriptor: Histone H3, Ubiquitin, ZINC ION, ... (12 entities in total)
• Functional Keywords: nucleosome modification, transcriptional regulation, gene regulation
• Biological source: Xenopus laevis (African clawed frog); More
• Total number of polymer chains: 15
• Total formula weight: 307848.18

Authors

Yu, Y.,Cai, D.,Zhang, Y.Z.,Huang, J. (deposition date: 2025-06-02, release date: 2026-06-10)

• Primary citation: Yu, Y.,Cai, D.,Zhang, Y.Z.,Huang, J.; Structural mechanisms of PRC1-mediated interplay between gene repression and activation; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.8 Å)