9V9C

Cryo-EM structure of human TNFR1 DD filament

Summary for 9V9C

• Entry DOI: 10.2210/pdb9v9c/pdb
• EMDB information: 64869
• Descriptor: Tumor necrosis factor receptor superfamily member 1A, membrane form (1 entity in total)
• Functional Keywords: death doamin, protein fibril
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 20
• Total formula weight: 260717.50

Authors

Zhao, K.,Liu, J.P.,Liu, C.,Yuan, J.Y. (deposition date: 2025-05-30, release date: 2026-04-08)

• Primary citation: Zhao, K.,Liu, J.P.,Liu, C.,Yuan, J.Y.; Electric dipole moment drives the dynamics of the TNFR1 complex I signalosome; Nature, 2026; DOI: 10.1038/s41586-026-10304-1

Experimental method

ELECTRON MICROSCOPY (2.62 Å)