9V6Q

Cryo-EM structure of two cPRC1 complexes bound to opposite faces of an endogenous 147-bp mono-nucleosome

Summary for 9V6Q

Entry DOI	10.2210/pdb9v6q/pdb
EMDB information	64804
Descriptor	Histone H3.1, Histone H2A type 1-H, Histone H2B type 1-C/E/F/G/I, ... (9 entities in total)
Functional Keywords	histone modification, transcriptional regulation, gene regulation
Biological source	Homo sapiens (human) More
Total number of polymer chains	14
Total formula weight	348566.18
Authors	Yu, Y.,Cai, D.,Zhang, Y.Z.,Huang, J. (deposition date: 2025-05-27, release date: 2026-06-10)
Primary citation	Yu, Y.,Cai, D.,Zhang, Y.Z.,Huang, J. Structural mechanisms of PRC1-mediated interplay between gene repression and activation To Be Published,
Experimental method	ELECTRON MICROSCOPY (4.6 Å)

Structure validation