9V5H

cryo-EM structure of hexameric ArnA

Summary for 9V5H

• Entry DOI: 10.2210/pdb9v5h/pdb
• Related: 1Z7E 4WKG 6PIH
• EMDB information: 64789
• Descriptor: Bifunctional polymyxin resistance protein ArnA (2 entities in total)
• Functional Keywords: lipid a modification polymyxin resistance bifunctional enzyme udp-glucuronic acid dehydrogenase udp-4-amino-4-deoxy-l-arabinose, transferase lipopolysaccharide biosynthesis antibiotic resistance aminotransferase dehydrogenase lps modification pathway l-ara4n biosynthesis, transferase
• Biological source: Escherichia coli; More
• Total number of polymer chains: 12
• Total formula weight: 434769.79

Authors

Caliseki, M.,Borucu, U.,Kadapalakere, S.Y.,Schaffitzel, C.,Kabasakal, B.V. (deposition date: 2025-05-26, release date: 2025-07-30)

• Primary citation: Caliseki, M.,Borucu, U.,Yadav, S.K.N.,Schaffitzel, C.,Kabasakal, B.V.; Off-Target Structural Insights: ArnA and AcrB in Bacterial Membrane Protein Cryo-EM Analysis; Biorxiv, 2025; DOI: 10.1101/2025.05.31.656883

Experimental method

ELECTRON MICROSCOPY (4 Å)