9UW3

The complex of human pMEK1 and ERK1 pY204 (ANP)

Summary for 9UW3

Entry DOI	10.2210/pdb9uw3/pdb
EMDB information	64544
Descriptor	Dual specificity mitogen-activated protein kinase kinase 1, Mitogen-activated protein kinase 3, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total)
Functional Keywords	mek1. erk1, complex, kinase, mapk pathway, transferase
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	90517.77
Authors	Peng, C.,Sun, Y.,Liu, S.,Zhou, F.,Hu, Q. (deposition date: 2025-05-12, release date: 2026-04-01)
Primary citation	Sun, Y.,Peng, C.,Liu, S.,Zhou, F.,Huang, G.,Wang, J.,Hu, Q. Mechanistic insight into the phosphorylation of ERK by MEK Biorxiv, 2026 Cited by DOI: 10.64898/2026.03.13.710243 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.36 Å)

Structure validation