9UVU

Cryo-EM structure of bradykinin B2 receptor (B2R)-BRIL/anti BRIL SRP2070 Fab antibody complex with icatibant, focused on receptor

This is a non-PDB format compatible entry.

Summary for 9UVU

• Entry DOI: 10.2210/pdb9uvu/pdb
• EMDB information: 64537
• Descriptor: icatibant, B2 bradykinin receptor,Soluble cytochrome b562 (2 entities in total)
• Functional Keywords: gpcr, b2r, bradykinin, icatibant, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 56147.40

Authors

Kojima, A.,Kawakami, K.,Kobayashi, K.,Matsui, T.E.,Gu, Y.,Fukuda, M.,Kato, H.E. (deposition date: 2025-05-11, release date: 2026-05-06)

• Primary citation: Kojima, A.,Kawakami, K.,Kobayashi, N.,Kobayashi, K.,Matsui, T.E.,Uemoto, K.,Gu, Y.,Fukuda, M.,Kato, H.E.; A Rapid and Universal Pipeline for High-Resolution GPCR Structure Determination through In Silico Construct Optimization and de novo Protein Design; Biorxiv, 2026; DOI: 10.64898/2026.04.02.716066

Experimental method

ELECTRON MICROSCOPY (3.69 Å)