9UIS

Cryo-EM structure of the prostaglandin D2 receptor 1 (DP1) bound to the antagonist asapiprant resolved via the fusion/crosslinking strategy

This is a non-PDB format compatible entry.

Summary for 9UIS

• Entry DOI: 10.2210/pdb9uis/pdb
• EMDB information: 64203
• Descriptor: Prostaglandin D2 receptor, Green fluorescent protein, GFP-clamp E186C, ... (4 entities in total)
• Functional Keywords: prostaglandin d2 receptor 1 (dp1); fusion/crosslinking strategy; asapiprant., membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 95068.15

Authors

Han, S.C.,Li, M.H. (deposition date: 2025-04-16, release date: 2026-10-28)

• Primary citation: Han, S.C.,Li, M.H.; Cryo-EM structure determination of GPCRs with disulfide-crosslinked fusion protein; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.75 Å)