9UIM

Cryo-EM structure of the human CB1 cannabinoid receptor bound to the inverse agonist taranabant resolved via the fusion/crosslinking strategy

Summary for 9UIM

• Entry DOI: 10.2210/pdb9uim/pdb
• EMDB information: 64197
• Descriptor: Cannabinoid receptor 1, Green fluorescent protein, GFP-clamp E186C, ... (4 entities in total)
• Functional Keywords: human cb1 cannabinoid receptor; fusion/crosslinking strategy; taranabant., membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 90247.32

Authors

Han, S.C.,Li, M.H. (deposition date: 2025-04-15, release date: 2026-10-28)

• Primary citation: Han, S.C.,Li, M.H.; Cryo-EM structure determination of GPCRs with disulfide-crosslinked fusion protein; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.06 Å)