9UG9

The cryo-EM structure of 26S proteasome-Midnolin complex MB state

This is a non-PDB format compatible entry.

Summary for 9UG9

• Entry DOI: 10.2210/pdb9ug9/pdb
• Related: 9M2W 9UF8
• EMDB information: 64133
• Descriptor: Midnolin, Proteasome subunit beta type-1, 26S proteasome regulatory subunit 6B, ... (37 entities in total)
• Functional Keywords: 26s proteasome, complex, midnolin, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 48
• Total formula weight: 1718865.30

Authors

Wang, H.Y.,Xu, W.Q. (deposition date: 2025-04-11, release date: 2025-09-10, Last modification date: 2026-07-01)

• Primary citation: Wang, H.,Zheng, Y.,Wang, T.,Zhang, X.,Wang, P.,Wei, C.,Li, H.,Wang, Q.,Zhang, L.,Ke, X.,Xu, W.; Structure-based engineering of the midnolin-proteasome pathway for targeted protein degradation.; Protein Cell, 17:83-88, 2026; PubMed: 40851512; DOI: 10.1093/procel/pwaf069

Experimental method

ELECTRON MICROSCOPY (3.5 Å)