9UG8

Cryo-EM structure of CDK2/CyclinE bound to a lysine covalent inhibitor

This is a non-PDB format compatible entry.

Summary for 9UG8

• Entry DOI: 10.2210/pdb9ug8/pdb
• EMDB information: 64132
• Descriptor: Cyclin-dependent kinase 2, G1/S-specific cyclin-E1 (2 entities in total)
• Functional Keywords: cdk2, cycline1, inhibitor, cell cycle
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 61850.24

Authors

Jia, S.,Li, S.,Wu, C.,Xu, H.E.,Ding, K.,Fan, M.,Ma, D. (deposition date: 2025-04-11, release date: 2026-10-28)

• Primary citation: Jia, S.,Li, S.,Wu, C.,Xu, H.E.,Ding, K.,Fan, M.,Ma, D.; Cryo-EM structure of Cdk2/CyclinE bound to a lysine covalent inhibitor; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.87 Å)