9UF8

The cryo-EM structure of 26S proteasome-Midnolin complex in the MA state

This is a non-PDB format compatible entry.

Summary for 9UF8

• Entry DOI: 10.2210/pdb9uf8/pdb
• Related: 9M2W 9UG9
• EMDB information: 64103
• Descriptor: Proteasome subunit beta type-6, Proteasome subunit alpha type-7, Proteasome subunit beta type-1, ... (35 entities in total)
• Functional Keywords: midnolin, 26s proteasome, complex, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 47
• Total formula weight: 1718012.49

Authors

Wang, H.Y.,Xu, W.Q.,Wei, C.C. (deposition date: 2025-04-10, release date: 2025-09-10, Last modification date: 2026-07-01)

• Primary citation: Wang, H.,Zheng, Y.,Wang, T.,Zhang, X.,Wang, P.,Wei, C.,Li, H.,Wang, Q.,Zhang, L.,Ke, X.,Xu, W.; Structure-based engineering of the midnolin-proteasome pathway for targeted protein degradation.; Protein Cell, 17:83-88, 2026; PubMed: 40851512; DOI: 10.1093/procel/pwaf069

Experimental method

ELECTRON MICROSCOPY (4.32 Å)