9UCZ

Cryo-EM structure of the R2Tg retrotransposon in complex with R2RNA and rDNA in the initiating target-primed reverse transcription state (ZF3/2 disordered)

Summary for 9UCZ

• Entry DOI: 10.2210/pdb9ucz/pdb
• EMDB information: 64056
• Descriptor: Reverse transcriptase-like protein, R2Tg 3'UTR RNA, 28S DNA top strand, ... (8 entities in total)
• Functional Keywords: retrotransposon, line, reverse transcriptase, endonuclease, rna binding protein, rna binding protein-rna-dna complex, dna binding protein
• Biological source: Taeniopygia guttata; More
• Total number of polymer chains: 5
• Total formula weight: 234309.29

Authors

Komatsu, D.,Hiraizumi, M.,Fujimatsu, K.,Yamada, S.,Yamashita, K.,Nishimasu, H. (deposition date: 2025-04-06, release date: 2026-10-14)

• Primary citation: Komatsu, D.,Nishimasu, H.; Structure mechanism of the avian R2 retrotransposon for programmable gene integration; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.61 Å)