9UCP

cryo-EM structure of M1 muscarinic acetylcholine receptor-alpha5 helix of G11 protein complex bound to iperoxo and nanobody Nb1B4

Summary for 9UCP

Entry DOI	10.2210/pdb9ucp/pdb
EMDB information	64050
Descriptor	M1 muscarinic acetylcholine receptor, de novo design protein, Guanine nucleotide-binding protein subunit alpha-11, Nanobody Nb1B4, ... (4 entities in total)
Functional Keywords	gpcr, active-state, nanobody, de novo protein, membrane protein/immune system, membrane protein-immune system complex
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	66434.04
Authors	Zhang, X.,Gao, K.,Liu, X. (deposition date: 2025-04-05, release date: 2025-10-29)
Primary citation	Zhang, X.,Gao, K.,Liu, X. cryo-EM structure of M1 muscarinic acetylcholine receptor-alpha5 helix of G11 protein complex bound to iperoxo and nanobody Nb1B4 To Be Published,
Experimental method	ELECTRON MICROSCOPY (2.88 Å)

Structure validation