9U8S

Crystal structure of thiamine pyrophosphate (TPP)-dependent alpha-imino acid decarboxylase (AzcB and AzcC) from Streptomyces mobaraensis in complex with TPP and 5-azacytosine.

Summary for 9U8S

• Entry DOI: 10.2210/pdb9u8s/pdb
• Descriptor: Thiamine pyrophosphate enzyme N-terminal TPP-binding domain-containing protein, Thiamine pyrophosphate enzyme TPP-binding domain-containing protein, 6-amino-1,3,5-triazin-2(1H)-one, ... (8 entities in total)
• Functional Keywords: thiamine pyrophosphate (tpp)-dependent decarboxylase, azcb, azcc, 5-azacytidine biosynthesis, 5-azacytosine, lyase
• Biological source: Streptomyces mobaraensis; More
• Total number of polymer chains: 12
• Total formula weight: 235128.30

Authors

Nakashima, Y.,Tsunoda, T.,Ogasawara, Y.,Dairi, T.,Morita, H. (deposition date: 2025-03-26, release date: 2026-04-01)

• Primary citation: Nakashima, Y.,Morita, H.; Crystal structure of thiamine pyrophosphate (TPP)-dependent decarboxylase (AzcB and AzcC complexes) from Streptomyces mobaraensis in complex with TPP and 5-azacytosine.; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.46 Å)