9U02

Medin fibril generated from the heterotypic interaction of Abeta40 and Medin.

Summary for 9U02

• Entry DOI: 10.2210/pdb9u02/pdb
• EMDB information: 56480
• Descriptor: Lactadherin (1 entity in total)
• Functional Keywords: medin, amyloid, aggregation, mfge8, neurodegeneration, protein fibril
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 10
• Total formula weight: 54349.45

Authors

Pradhan, B.,Kumar, S.T.,Wagner, J.,Gallardo, R.,Zorzini, V.,Orlando, G.,Vleeschouwer, M.D.,Madine, J.,Louros, N.,Neher, J.,Schymkowitz, J.,Rousseau, F. (deposition date: 2026-01-26, release date: 2026-04-08)

• Primary citation: Pradhan, B.,Kumar, S.T.,Wagner, J.,Gallardo, R.,Zorzini, V.,Orlando, G.,Vleeschouwer, M.D.,Madine, J.,Louros, N.,Neher, J.,Schymkowitz, J.,Rousseau, F.; Medin drives Abeta40 to adopt Abeta42-like fibril polymorphs in vitro; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.7 Å)