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9TXL

ITIH4N:MASP-1cf:12A12 F(ab) 2:1:2 complex (Composite)

Summary for 9TXL
Entry DOI10.2210/pdb9txl/pdb
EMDB information56404
DescriptorIsoform 3 of Inter-alpha-trypsin inhibitor heavy chain H4, Ligand glutamate from MASP-1cf, 12A12 mAb F(ab) heavy chain, ... (9 entities in total)
Functional Keywordsprotease inhibitor, plasma protein, complement, coagulation, contact cascade, immune system
Biological sourceHomo sapiens (human)
More
Total number of polymer chains7
Total formula weight238169.04
Authors
Joergensen, M.H.,Andersen, G.R. (deposition date: 2026-01-15, release date: 2026-09-23)
Primary citationJoergensen, M.H.,Andersen, G.R.
The plasma protease inhibitor ITIH4 forms oligomeric complexes and senses broader, proteolytic activity
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.3 Å)
Structure validation
No wwPDB Validation report is currently available for this entry.

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