9TTA

Crystal Structure of S12 bound to Ck2a

This is a non-PDB format compatible entry.

Summary for 9TTA

• Entry DOI: 10.2210/pdb9tta/pdb
• Descriptor: Casein kinase II subunit alpha, 3-[2-[4-[(3-chloranyl-4-phenyl-phenyl)methylamino]butyl-[2-oxidanylidene-2-[2-(2-prop-2-ynoxyethoxy)ethylamino]ethyl]amino]ethanoylamino]benzoic acid, ACETATE ION, ... (4 entities in total)
• Functional Keywords: protacs, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 39739.61

Authors

Brear, P.,Day-Riley, S.,Krajcovicov, S.,Raj Sokha, A.,Venne, J.,Hyvonen, M.,Whitehurst, B.,Spring, D.R. (deposition date: 2026-01-06, release date: 2026-05-06, Last modification date: 2026-05-13)

• Primary citation: Day-Riley, S.,Krajcovicov, S.,Brear, P.,Raj Sokha, A.,Venne, J.,Hyvonen, M.,Whitehurst, B.,Spring, D.R.; Towards the Targeted Protein Degradation of CK2: Design and Synthesis of CAM4066-Based PROTACs; To be published,

Experimental method

X-RAY DIFFRACTION (1.91 Å)