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9TOH

Room temperature serial crystal structure of CTX-M-15 class A beta-lactamase mixed with avibactam for 600 s

Summary for 9TOH
Entry DOI10.2210/pdb9toh/pdb
DescriptorBeta-lactamase, CHLORIDE ION, SODIUM ION, ... (6 entities in total)
Functional Keywordsantibiotic resistance, beta-lactamase, inhibitor, dynamics, tr-ssx, antimicrobial protein
Biological sourceKlebsiella pneumoniae
Total number of polymer chains1
Total formula weight28883.94
Authors
Tooke, C.L.,Hinchliffe, P.,Spencer, J. (deposition date: 2025-12-16, release date: 2026-10-28)
Primary citationTooke, C.L.,Hinchliffe, P.,Orville, A.M.,Spencer, J.
Time-resolved ligand dynamics revealed in a beta-lactamase using room-temperature serial crystallography
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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PDB entries from 2026-10-28

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