9TOF

CTX-M-15 class A beta-lactamase mixed with avibactam for 3 hours, then washed for 300 s, cryo crystal structure

Summary for 9TOF

• Entry DOI: 10.2210/pdb9tof/pdb
• Descriptor: Beta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, GLYCEROL, ... (7 entities in total)
• Functional Keywords: antibiotic resistance, beta-lactamase, inhibitor, dynamics, antimicrobial protein
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 1
• Total formula weight: 29118.03

Authors

Tooke, C.L.,Hinchliffe, P.,Spencer, J. (deposition date: 2025-12-16, release date: 2026-10-28)

• Primary citation: Tooke, C.L.,Hinchliffe, P.,Orville, A.M.,Spencer, J.; Time-resolved ligand dynamics revealed in a beta-lactamase using room-temperature serial crystallography; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.24 Å)