9TO6

Room temperature serial crystal structure of CTX-M-15 class A beta-lactamase, drop on fixed target from DLS, 1.3 s mixed with 300 mM avibactam

Summary for 9TO6

Entry DOI	10.2210/pdb9to6/pdb
Descriptor	Beta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (2S,5R)-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide, ... (6 entities in total)
Functional Keywords	antibiotic resistance, beta-lactamase, inhibitor, dynamics, tr-ssx, antimicrobial protein
Biological source	Klebsiella pneumoniae
Total number of polymer chains	1
Total formula weight	28906.93
Authors	Parkinson, L.,Tooke, C.L.,Hinchliffe, P.,Beer, M.,Spencer, J. (deposition date: 2025-12-16, release date: 2026-10-28, Last modification date: 2026-11-11)
Primary citation	Parkinson, L.,Tooke, C.L.,Hinchliffe, P.,Beer, M.,Orville, A.M.,Spencer, J. To Be Published To Be Published, Cited by DOI: 10.1038/s42004-026-02262-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.62 Å)

Structure validation