9TO3

Room temperature serial crystal structure of CTX-M-15 class A beta-lactamase, drop on fixed target from PAL-XFEL, 1.3 s mixed with avibactam

Summary for 9TO3

• Entry DOI: 10.2210/pdb9to3/pdb
• Descriptor: Beta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (2S,5R)-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide, ... (6 entities in total)
• Functional Keywords: antibiotic resistance, beta-lactamase, inhibitor, dynamics, tr-sfx, xfel, antimicrobial protein
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 1
• Total formula weight: 28906.93

Authors

Hinchliffe, P.,Tooke, C.L.,Beer, M.,Spencer, J. (deposition date: 2025-12-16, release date: 2026-10-28, Last modification date: 2026-11-11)

• Primary citation: Hinchliffe, P.,Tooke, C.L.,Beer, M.,Orville, A.M.,Spencer, J.; To Be Published; To Be Published, ; DOI: 10.1038/s42004-026-02262-6

Experimental method

X-RAY DIFFRACTION (1.45 Å)