9TJT

Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and the benzoxaborole cmpd6 in the pre-activation state

Summary for 9TJT

• Entry DOI: 10.2210/pdb9tjt/pdb
• Descriptor: Leucine--tRNA ligase, tRNA(leu), ZINC ION, ... (6 entities in total)
• Functional Keywords: leucine trna ligase antimicrobial target trna aminoacylation for protein translation, rna binding protein
• Biological source: Escherichia coli; More
• Total number of polymer chains: 2
• Total formula weight: 128137.23

Authors

Hoffmann, G.,Palencia, A. (deposition date: 2025-12-08, release date: 2026-08-05)

• Primary citation: Hoffmann, G.,Dulic, M.,Gruic-Sovulj, I.,Palencia, A.; The Zn Domain Acts as a Dynamic Switch Coordinating Multiple-Step Aminoacylation in Bacterial Leucyl-tRNA Synthetase; Nucleic Acids Res., 2026; DOI: 10.1093/nar/gkag786

Experimental method

X-RAY DIFFRACTION (2.87 Å)