9TE5

Cryo-EM structure of C5*-CVFBb (state 2.0)

Summary for 9TE5

• Entry DOI: 10.2210/pdb9te5/pdb
• EMDB information: 55820
• Descriptor: Complement C5 beta chain, Complement C5 alpha chain, Cobra venom factor alpha chain, ... (6 entities in total)
• Functional Keywords: complement, proteolysis, cobra, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 328413.47

Authors

Joergensen, M.H.,Andersen, G.R.,Almeida, A.V.d. (deposition date: 2025-11-25, release date: 2026-10-28)

• Primary citation: Joergensen, M.H.,Andersen, G.R.,Almeida, A.V.d.; Cryo-EM analysis of complement C5-convertase complex reveals major proteolysis independent substrate rearrangements and a trans-geometry of convertase; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.09 Å)