9TAU

De novo photoenzyme variant ABLE-E116C-TXT V111H-L53A (photoABLE2 precursor) in complex with substrate

This is a non-PDB format compatible entry.

Summary for 9TAU

• Entry DOI: 10.2210/pdb9tau/pdb
• Descriptor: De novo photoenzyme variant ABLE, 3-but-3-enoxy-1~{H}-quinolin-2-one, SODIUM ION, ... (4 entities in total)
• Functional Keywords: photoenzym, de novo protein scaffold, thioxanthon, [2+2] photocycloaddition, de novo protein
• Biological source: synthetic construct
• Total number of polymer chains: 1
• Total formula weight: 14026.69

Authors

Boesen, B.,Heider, A.,O'Shea, J.M.,Groll, M.,Bach, T.,Zeymer, C. (deposition date: 2025-11-18, release date: 2026-03-25)

• Primary citation: Boesen, B.,Heider, A.,O’Shea, J.M.,Groll, M.,Bach, T.,Zeymer, C.; Enantiodivergent Evolution of a De Novo Protein for Enzymatic [2 + 2] Photocycloaddition Activity; ACS Catal., 2026; DOI: 10.1021/acscatal.5c08946

Experimental method

X-RAY DIFFRACTION (1.4 Å)