9T94
cryo-EM structure of AKT phosphorylated mTOR complex 2, focused on a single protomer
Summary for 9T94
| Entry DOI | 10.2210/pdb9t94/pdb |
| Related | 9T7J |
| EMDB information | 55716 |
| Descriptor | Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8, Rapamycin-insensitive companion of mTOR, ... (8 entities in total) |
| Functional Keywords | kinase, complex, signaling protein, transferase |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 585861.16 |
| Authors | Hay, I.M.,Anandapadamanaban, M.,Williams, R.L. (deposition date: 2025-11-13, release date: 2026-04-22) |
| Primary citation | Hay, I.M.,Bourguet, M.,Ahsan, B.,Perisic, O.,Anandapadamanaban, M.,Williams, R.L. Structural basis for a phosphoinositide-driven mTORC2-AKT positive feedback loop Biorxiv, 2026 Cited by DOI: 10.64898/2026.01.08.698367PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.6 Å) |
Structure validation
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