9T8E

Crystal structure of lurbinectedin bound to 10-mer duplex DNA

This is a non-PDB format compatible entry.

Summary for 9T8E

• Entry DOI: 10.2210/pdb9t8e/pdb
• Descriptor: DNA (5'-D(*CP*GP*AP*TP*GP*CP*AP*TP*CP*G)-3'), POTASSIUM ION, Lurbinectedin, ... (5 entities in total)
• Functional Keywords: ecteinascidin, dna duplex, covalent bond, dna
• Biological source: DNA molecule
• Total number of polymer chains: 2
• Total formula weight: 7155.42

Authors

Darriere, T.,Ruiz, F.M.,Cuevas, C.,Fernandez-Tornero, C. (deposition date: 2025-11-12, release date: 2026-07-29)

• Primary citation: Darriere, T.,Ruiz, F.M.,Martinez-Diez, M.,Lima Ribeiro, M.,Cuevas, C.,Fernandez-Tornero, C.; The structures of ecteinascidins bound to DNA shed light on their mechanism of action; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)