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9T74

2'-fluoro-modified pyrimidine (FY) RNA aptamer binding to the receptor binding domain (RBD) of the SARS-CoV-2 spike protein. (focus map: RBD-aptamer)

Summary for 9T74
Entry DOI10.2210/pdb9t74/pdb
EMDB information55625
DescriptorDNA/RNA (51-MER), Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywordsorigami, modified nucleic acids, xna, rna, aptamer, 2'fluoro
Biological sourcesynthetic RNA
More
Total number of polymer chains2
Total formula weight142164.93
Authors
Kristoffersen, E.L.,Andersen, E.S.,Zwergious, N.H. (deposition date: 2025-11-10, release date: 2026-03-04)
Primary citationKristoffersen, E.L.,Zwergius, N.H.,Vallina, N.S.,Gluck, N.,Stange, A.,Desdorf, L.,Civit, L.,Geary, C.,Kjems, J.,Valero, J.,Andersen, E.S.
Serum-stable RNA origami nano-devices
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.46 Å)
Structure validation

250059

PDB entries from 2026-03-04

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