9T35

Cryo-EM structure of homo-hexameric hLRRC8A L402W

Summary for 9T35

• Entry DOI: 10.2210/pdb9t35/pdb
• EMDB information: 55484
• Descriptor: Volume-regulated anion channel subunit LRRC8A (1 entity in total)
• Functional Keywords: volume-regulated anion channel, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 6
• Total formula weight: 566511.14

Authors

Bertelli, S.,Wang, L.,Klussendorf, M.,Pusch, M.,Dutzler, R.,Stauber, T. (deposition date: 2025-10-24, release date: 2026-09-09)

• Primary citation: Bertelli, S.,Wang, L.,Klussendorf, M.,Pusch, M.,Dutzler, R.,Stauber, T.; The intracellular subdomain of the volume regulated anion channel subunit LRRC8A is a hotspot of channel activation; To Be Published, 2026; DOI: 10.1038/s41467-026-77507-y

Experimental method

ELECTRON MICROSCOPY (2.78 Å)