9T2I

SP100 nuclear antigen with crystallization epitope mutations N816D:T820R

Summary for 9T2I

• Entry DOI: 10.2210/pdb9t2i/pdb
• Descriptor: Isoform Sp100-C of Nuclear autoantigen Sp-100, ZINC ION (3 entities in total)
• Functional Keywords: crystal epitopes, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 42921.74

Authors

Fairhead, M.,Strain-Damerell, C.,Ye, M.,Mackinnon, S.R.,Pinkas, D.,MacLean, E.M.,Koekemoer, L.,Damerell, D.,Krojer, T.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Yue, W.,Burgess-Brown, N.,Marsden, B.,von Delft, F. (deposition date: 2025-10-22, release date: 2026-02-25)

• Primary citation: Fairhead, M.,Strain-Damerell, C.,Ye, M.,Mackinnon, S.R.,Pinkas, D.,MacLean, E.M.,Koekemoer, L.,Damerell, D.,Krojer, T.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Yue, W.,Burgess-Brown, N.,Marsden, B.,von Delft, F.; A fast, parallel method for efficiently exploring crystallization behaviour of large numbers of protein variants; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.35 Å)