9SYZ

Crystal structure of PD-2020 bound METTL3-METTL14 complex

This is a non-PDB format compatible entry.

Summary for 9SYZ

• Entry DOI: 10.2210/pdb9syz/pdb
• Descriptor: N(6)-adenosine-methyltransferase catalytic subunit METTL3, N(6)-adenosine-methyltransferase non-catalytic subunit METTL14, ~{N}-[1-[4-[(cyclobutylmethylamino)methyl]phenyl]piperidin-4-yl]-4-oxidanylidene-pyrido[1,2-a]pyrimidine-2-carboxamide, ... (4 entities in total)
• Functional Keywords: mettl3, mettl14, n6-methyladenosine, modification of rna, ligand, rna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 59841.37

Authors

Benysek, J.,Boura, E. (deposition date: 2025-10-14, release date: 2026-11-04)

• Primary citation: Benysek, J.,Boura, E.; Crystal structure of PD-2016 bound METTL3-METTL14 complex; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.13 Å)