9SYM

Structure of human DNMT2 with bound competitive inhibitor

This is a non-PDB format compatible entry.

Summary for 9SYM

• Entry DOI: 10.2210/pdb9sym/pdb
• Descriptor: tRNA (cytosine(38)-C(5))-methyltransferase, (2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[3-(4-azanyl-2-oxidanylidene-1~{H}-pyrimidin-5-yl)propyl]amino]-2-azanyl-butanoic acid, GLYCINE, ... (7 entities in total)
• Functional Keywords: methyl transferase, trna methylation, competitive inhibitor, drug design, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 40984.18

Authors

Schwan, M.,Kopp, J.,Sinning, I. (deposition date: 2025-10-13, release date: 2026-10-28)

• Primary citation: Schwan, M.,Kopp, J.,Sinning, I.; Structure of human DNMT2 with bound competitive inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)