9SYL

Structure of human DNMT2 with bound competitive inhibitor

This is a non-PDB format compatible entry.

Summary for 9SYL

• Entry DOI: 10.2210/pdb9syl/pdb
• Descriptor: tRNA (cytosine(38)-C(5))-methyltransferase, (2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[(2-phenylphenyl)methyl]amino]-2-azanyl-butanoic acid, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: methyl transferase, trna methylation, competitive inhibitor, drug design, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 40914.04

Authors

Schwan, M.,Kopp, J.,Sinning, I. (deposition date: 2025-10-13, release date: 2026-10-28)

• Primary citation: Schwan, M.,Kopp, J.,Sinning, I.; Structure of human DNMT2 with bound inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)