9SXE

c-KIT kinase domain in complex with AZD7762

Summary for 9SXE

• Entry DOI: 10.2210/pdb9sxe/pdb
• Descriptor: Mast/stem cell growth factor receptor Kit, 5-(3-fluorophenyl)-N-[(3S)-3-piperidyl]-3-ureido-thiophene-2-carboxamide (3 entities in total)
• Functional Keywords: c-kit, protein kinase, inhibitor, tyrosine kinase, transmembrane receptor, stem cell factor, stem cell factor receptor, gist, gastrointestinal stromal tumors, p10721, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 75113.70

Authors

Teuber, A.,Kleinboelting, S.B.,Mueller, M.P.,Rauh, D. (deposition date: 2025-10-09, release date: 2026-10-21)

• Primary citation: Muehlenberg, T.,Teuber, A.,Kleinboelting, S.B.,Mueller, M.P.,Rauh, D.; c-KIT kinase domain in complex with AZD7762; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.33 Å)