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9SWZ

Structure of MM762(D10A)-sgRNA/DNA ternary complex

Summary for 9SWZ
Entry DOI10.2210/pdb9swz/pdb
EMDB information55328
DescriptorMM762, RNA (141-MER), DNA (35-MER), ... (4 entities in total)
Functional Keywordscrispr-cas, antiviral protein
Biological sourcesynthetic construct
More
Total number of polymer chains4
Total formula weight147521.35
Authors
Ekundayo, B.E.,Ni, D.C.,Stahlberg, H. (deposition date: 2025-10-08, release date: 2026-10-28)
Primary citationKong, X.,Xue, Y.,Li, G.,Li, J.,Ekundayo, B.,Chen, Y.,Yang, K.,Lin, J.,Wu, M.,Wang, Y.,Liu, K.,Wang, Y.,Xia, J.,Bai, W.,Yang, D.,Zhang, H.,Liu, Y.,Li, T.,Shi, Y.,Stahlberg, H.,Zhou, X.,Huang, J.,Ni, D.,Zhou, Y.,Yang, H.
Overcoming Cas-dependent off-target and delivery barriers in base editing via an engineered type II-D Cas system
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.02 Å)
Structure validation

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