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9SW8

Crystal structure of human carbonic anhydrase II in complex with 4-(4-((4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)phenyl)sulfonyl)-1,4-diazepan-1-yl)-3-fluorobenzenesulfonamide

This is a non-PDB format compatible entry.
Summary for 9SW8
Entry DOI10.2210/pdb9sw8/pdb
DescriptorCarbonic anhydrase 2, GLYCEROL, 1,2-ETHANEDIOL, ... (6 entities in total)
Functional Keywordscarbonic anhydrase ii; metalloenzyme, sildenafil, sulfonamide, inhibitor, lyase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight30156.37
Authors
Angeli, A.,Ferraroni, M. (deposition date: 2025-10-04, release date: 2026-10-14)
Primary citationAngeli, A.,Ferraroni, M.
Crystal structure of human carbonic anhydrase II in complex with 4-(4-((4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)phenyl)sulfonyl)-1,4-diazepan-1-yl)-3-fluorobenzenesulfonamide
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.107 Å)
Structure validation

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PDB entries from 2026-10-21

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