9SSR

Human Methionine Synthase With Methyltetrahydrofolate, Hydroxocobalamin, and SAM, N-Half From Full-Length

Summary for 9SSR

• Entry DOI: 10.2210/pdb9ssr/pdb
• EMDB information: 55192
• Descriptor: Methionine synthase, N-[4-({[(6S)-2-AMINO-4-HYDROXY-5-METHYL-5,6,7,8-TETRAHYDROPTERIDIN-6-YL]METHYL}AMINO)BENZOYL]-L-GLUTAMIC ACID (2 entities in total)
• Functional Keywords: methionine, folate, cobalamin, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 141155.22

Authors

Ferreira, D.S.M.,Yue, W.W.,McCorvie, T.J. (deposition date: 2025-09-26, release date: 2025-10-15)

• Primary citation: Ferreira, D.S.M.,Yue, W.W.,McCorvie, T.J.; Structural insights into cobalamin loading and reactivation of human methionine synthase; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.84 Å)