9SR0

Mouse vinculin head domain 1 (VD1) (residues 2-258) with A50I mutation in complex with mouse talin 1 helix 50 (H50, residues 2072-2103)

Summary for 9SR0

• Entry DOI: 10.2210/pdb9sr0/pdb
• Descriptor: Vinculin, Talin-1 (3 entities in total)
• Functional Keywords: vinculin, talin, vinculin binding site, focal adhesions, a50i, cell adhesion
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 32364.25

Authors

Kallem, T.,Goult, B.T.,Ball, N.J. (deposition date: 2025-09-23, release date: 2026-05-20)

• Primary citation: Kallem, T.,Guo, Y.,Reynolds, M.K.,Ball, N.J.,Athale, M.,Baker, K.B.,Mykuliak, V.V.,Ek, F.,Aldaz-Casanova, S.,Turkki, P.,Hytonen, V.P.,Brown, N.H.,Hoffman, B.D.,Yan, J.,Goult, B.T.; Talin controls the spatial distribution of vinculin tension in focal adhesions; Biorxiv, 2026; DOI: 10.64898/2026.05.07.722930

Experimental method

X-RAY DIFFRACTION (1.49 Å)