9SQG

PaMurU in complex with Mn2+ and UDPNAM (uridine diphosphate N-acetyl muramic acid)

Summary for 9SQG

• Entry DOI: 10.2210/pdb9sqg/pdb
• Related: 9SMV
• Descriptor: N-acetylmuramate alpha-1-phosphate uridylyltransferase, (2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoic acid, CHLORIDE ION, ... (7 entities in total)
• Functional Keywords: pseudonomas aeruginosa peptidoglycan recycling pathway bacteria cell wall, transferase
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 3
• Total formula weight: 80988.56

Authors

Jimenez-Faraco, E.,Hermoso, J.A. (deposition date: 2025-09-22, release date: 2026-07-29)

• Primary citation: Jimenez-Faraco, E.,El-Araby, A.M.,Feltzer, R.,Nguyen, V.T.,Mobashery, S.,Hermoso, J.A.; Catalytic Cycle of N-Acetylmuramic Acid-alpha-1-Phosphate Uridylyltransferase MurU of Pseudomonas aeruginosa; Acs Catalysis, 2026; DOI: 10.1021/acscatal.6c01767

Experimental method

X-RAY DIFFRACTION (1.85 Å)