9SQ5

Cryo-EM structure of the DDB1deltaB-CRBN-Pomalidomide complex bound to IKZF1(ZF1-ZF2-Helix)

Summary for 9SQ5

• Entry DOI: 10.2210/pdb9sq5/pdb
• EMDB information: 55107
• Descriptor: DNA damage-binding protein 1, Protein cereblon, Isoform Ik7 of DNA-binding protein Ikaros, ... (5 entities in total)
• Functional Keywords: ligase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 162517.04

Authors

Galli, P.,Kater, L.,Kempf, G.,Cavadini, S.,Thoma, N.H. (deposition date: 2025-09-19, release date: 2026-06-17)

• Primary citation: Galli, P.,Thoma, N.H.; Cryo-EM structure of the DDB1deltaB-CRBN-Pomalidomide complex bound to IKZF1(ZF1-ZF2-Helix); To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.68 Å)