9SPC

Recombinant human butyrylcholinesterase in complex with ethyl 1-[3-(2-oxopyrrolidin-1-yl)propyl]-2-phenyl-1H-1,3-benzodiazole-5-carboxylate

This is a non-PDB format compatible entry.

Summary for 9SPC

• Entry DOI: 10.2210/pdb9spc/pdb
• Descriptor: Cholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• Functional Keywords: butyrylcholinesterase, inhibitor, complex, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 63473.00

Authors

Brazzolotto, X.,Ha, Z.Y.,Law, C.S.W.,Yeong, K.Y. (deposition date: 2025-09-16, release date: 2026-02-18)

• Primary citation: Law, C.S.W.,Ha, Z.Y.,Brazzolotto, X.,Yeong, K.Y.; Structure-Guided Design and Synthesis of Selective Butyrylcholinesterase Inhibitors; J.Mol.Struct., :145611-, 2026; DOI: 10.1016/j.molstruc.2026.145611

Experimental method

X-RAY DIFFRACTION (2.66 Å)