9SLU

human GSTA1 in complex with dendrogenin A (bilary salt analogue, 3beta,5alpha-dihydroxy-6beta-[2-(1H-imidazol-4-yl)-ethylamino]-cholan-24-oic acid)

This is a non-PDB format compatible entry.

Summary for 9SLU

• Entry DOI: 10.2210/pdb9slu/pdb
• Descriptor: Glutathione S-transferase A1, (4~{R})-4-[(3~{S},5~{R},6~{R},8~{S},9~{S},10~{R},13~{R},14~{S},17~{R})-6-[2-(4~{H}-imidazol-5-yl)ethylamino]-10,13-dimethyl-3,5-bis(oxidanyl)-1,2,3,4,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid (3 entities in total)
• Functional Keywords: gluathione s transferase complexe dendrogenin a, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 52343.64

Authors

Ndikoum-Matip, G.,Ayadi, S.,Poirot, M.,Nahoum, V.,Maveyraud, L. (deposition date: 2025-09-05, release date: 2026-09-16)

• Primary citation: Ayadi, S.,de Medina, P.,Lacroix-Triki, M.,Bunay, J.,Voisin, M.,Pucheu, L.,Sjodin, B.,Gadaleta, E.,Chelala, C.,Kim, H.Y.H.,Franchet, C.,Allal, B.,Filleron, T.,le Faouder, P.,Mourey, L.,Vija, L.,Porter, N.A.,Mannervik, B.,Nahoum, V.,Maveyraud, L.,Silvente-Poirot, S.,Poirot, M.; The tumor-suppressor cholesterol metabolite dendrogenin A is produced by glutathione transferase A1-1; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.675 Å)