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9SAH

Structure of a fusion of biosynthetic proteins E4 and NB2

Summary for 9SAH
Entry DOI10.2210/pdb9sah/pdb
DescriptorE4-NB2 synthetic fusion protein, DI(HYDROXYETHYL)ETHER (3 entities in total)
Functional Keywordsalpharep, artificial protein, binding hot spot, biosynthetic protein
Biological sourcesynthetic construct
Total number of polymer chains2
Total formula weight107965.73
Authors
Li de la Sierra-Gallay, I.,Mesneau, A. (deposition date: 2025-08-07, release date: 2026-08-19)
Primary citationGomes, M.,Mesneau, A.,Degaugue, A.,Gourmelon, F.,Raoudha, D.,Villain, D.,Noiray, M.,Aumont-Nicaise, M.,Li la Sierra-Gallay, I.,Minard, P.,Valerio-Lepiniec, M.,Urvoas, A.
Hot spot induction allows selection of protein binders targeted to a predefined region of a bait protein
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

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