9S8I

Crystal Structure of UDP-N-acetylmuramate-L-alanine ligase (MurC) from Pseudomonas aeruginosa in complex with compound OSA_001176 (WYH78)

Summary for 9S8I

• Entry DOI: 10.2210/pdb9s8i/pdb
• Descriptor: UDP-N-acetylmuramate--L-alanine ligase, (1R,2S)-1-({4-[(5-tert-butyl-1-methyl-1H-pyrazol-3-yl)amino]-1H-pyrazolo[3,4-d]pyrimidin-6-yl}amino)-2,3-dihydro-1H-inden-2-ol, PHOSPHATE ION, ... (8 entities in total)
• Functional Keywords: dimer, inhibitor, biosynthetic protein
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 2
• Total formula weight: 108519.00

Authors

Diaz-Saez, L.,Lloyd, A.J.,Wang, Y.,Todd, M.H.,Dowson, C.G. (deposition date: 2025-08-05, release date: 2025-09-17)

• Primary citation: Diaz-Saez, L.,Lloyd, A.J.,Wang, Y.,Todd, M.H.,Dowson, C.G.; Crystal Structure of UDP-N-acetylmuramate-L-alanine ligase (MurC) from Pseudomonas aeruginosa in complex with compound OSA_001176 (WYH78); To Be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)