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9S8D

Cryo-EM structure of Rat NHE6 in detergent

This is a non-PDB format compatible entry.
Summary for 9S8D
Entry DOI10.2210/pdb9s8d/pdb
EMDB information54660
DescriptorSodium/hydrogen exchanger 6, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, [(2~{S})-2-hexadecanoyloxy-3-[oxidanyl-[(1~{S},2~{R},3~{S},4~{S},5~{R},6~{R})-2,3,4,6-tetrakis(oxidanyl)-5-phosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] hexadecanoate, ... (4 entities in total)
Functional Keywordsna+/h+ exchanger, nhe6, transport protein
Biological sourceRattus norvegicus (Norway rat)
Total number of polymer chains2
Total formula weight160878.66
Authors
Yeo, H.,Jung, S.,Reichenbach, T.,Kokane, S.,Gulati, A.,Drew, D. (deposition date: 2025-08-05, release date: 2026-07-29)
Primary citationJung, S.,Yeo, H.,Reichenbach, T.,Kokane, S.,Gulati, A.,Albano, G.,Kirschbaum, C.,Manh Ho, T.,Li, H.,Landreh, M.,Abramsson, M.,Robinson, C.,Fuster, D.,Drew, D.
Structure of NHE6 and its lipid-mediated interactions regulating endosomal pH
To Be Published,
Experimental method
ELECTRON MICROSCOPY (2.74 Å)
Structure validation

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