9S8C

Cryo-EM structure of Rat NHE6 D293A variant

This is a non-PDB format compatible entry.

Summary for 9S8C

• Entry DOI: 10.2210/pdb9s8c/pdb
• EMDB information: 54659
• Descriptor: Sodium/hydrogen exchanger 6, [(2~{S})-2-hexadecanoyloxy-3-[oxidanyl-[(1~{S},2~{R},3~{S},4~{S},5~{R},6~{R})-2,3,4,6-tetrakis(oxidanyl)-5-phosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] hexadecanoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ... (5 entities in total)
• Functional Keywords: na+/h+ exchanger, nhe6, transport protein
• Biological source: Rattus norvegicus (Norway rat)
• Total number of polymer chains: 2
• Total formula weight: 163948.24

Authors

Jung, S.,Gulati, A.,Reichenbach, T.,Kokane, S.,Yeo, H.,Drew, D. (deposition date: 2025-08-05, release date: 2026-07-29)

• Primary citation: Jung, S.,Yeo, H.,Kokane, S.,Reichenbach, T.,Gulati, A.,Albano, G.,Kirschbaum, C.,Manh Ho, T.,Li, H.,Landreh, M.,Abramsson, M.,Robinson, C.,Fuster, D.,Drew, D.; Structure of NHE6 and its lipid-mediated interactions regulating endosomal pH; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.28 Å)