9S7A

Structure of protein kinase CK2alpha mutant R80C associated with the Okur-Chung Neurodevelopmental Syndrome

Summary for 9S7A

• Entry DOI: 10.2210/pdb9s7a/pdb
• Descriptor: Casein kinase II subunit alpha, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION, ... (5 entities in total)
• Functional Keywords: okur-chung neurodevelopmental syndrome, ocnds, protein kinase, ck2, casein kinase ck2, csnk2a1, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 96697.67

Authors

Werner, C.,Gast, A.,Meyer, S.C.,Jose, J.,Niefind, K. (deposition date: 2025-08-04, release date: 2026-08-19)

• Primary citation: Werner, C.,Gast, A.,Caefer, D.,Fellhoefer, J.M.,Jordan, S.,Buchwald, L.M.,Meyer, S.C.,Than, T.L.,Schwartz, D.,Jose, J.,Niefind, K.; Investigation of the structure-dysfunction relationship of various OCNDS-related CK2alpha mutants; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.03 Å)