9S61

Crystal structure of Aurora-A bound to DBL8

Summary for 9S61

• Entry DOI: 10.2210/pdb9s61/pdb
• Descriptor: DBL8, Aurora kinase A, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: kinase, complex, designed, inhibitor, transferase
• Biological source: synthetic construct; More
• Total number of polymer chains: 2
• Total formula weight: 40736.32

Authors

Miles, J.A.,Bayliss, R.W. (deposition date: 2025-07-30, release date: 2026-07-22)

• Primary citation: Miles, J.A.,Schiffrin, B.,Holder, J.,Wallis, E.J.,Manfield, I.W.,Burnap, S.A.,Struwe, W.B.,Gergely, F.,Bayliss, R.; Selective miniprotein inhibitors of Aurora-A kinase designed using interaction-motif scaffolding; Biorxiv, 2026; DOI: 10.64898/2026.07.12.737516

Experimental method

X-RAY DIFFRACTION (2.369 Å)