9S3I

Crystal structure of the human tumor necrosis factor receptor 1 extracellular domain at 1.64A resolution

Summary for 9S3I

• Entry DOI: 10.2210/pdb9s3i/pdb
• Descriptor: Tumor necrosis factor receptor superfamily member 1A, membrane form, PHOSPHATE ION (3 entities in total)
• Functional Keywords: transmembrane signaling receptor, extracellular domain, cytokine-mediated activity, immune regulation, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 37696.78

Authors

Povlsen, K.,Bach, A.,Gajhede, M.,Narayanan, D. (deposition date: 2025-07-24, release date: 2026-07-01)

• Primary citation: Chedotal, H.,Povlsen, K.,Narayanan, D.,Gotfredsen, C.,Gajhede, M.,Bach, A.,Clausen, M.; Discovery of ligands for the TNFR1 extracellular domain using fragment-based drug discovery; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.64 Å)