9S0R

Cryo-EM structure of human NHE6 in C1 symmetry

Summary for 9S0R

• Entry DOI: 10.2210/pdb9s0r/pdb
• EMDB information: 54418
• Descriptor: Sodium/hydrogen exchanger 6 (1 entity in total)
• Functional Keywords: nhe, c1 symmetry, homodimer, transporter, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 155977.02

Authors

Feilen, L.P.,Sach, L.,Tranchant, E.E.,Lalic, M.R.,Havelund, J.F.,Brauer, C.M.,Ginsthofer, M.,Ostendorf, J.,Ma, L.,Morrow, E.M.,Faergeman, N.J.,Pedersen, S.F.,Kragelund, B.B.,Autzen, H.E. (deposition date: 2025-07-16, release date: 2026-07-29)

• Primary citation: Feilen, L.P.,Sach, L.,Tranchant, E.E.,Lalic, M.R.,Havelund, J.F.,Brauer, C.M.,Ginsthofer, M.,Ostendorf, J.,Ma, L.,Morrow, E.M.,Faergeman, N.J.,Pedersen, S.F.,Kragelund, B.B.,Autzen, H.E.; Integrative structural analysis of the human endosomal Na/H exchanger NHE6 reveals lipid-modulated gating of the ion-binding site; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.5 Å)